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Preseptal Cellulitis vs Orbital Cellulitis

Dr Ben Wild

Overview

The orbital fossa (eye socket) contains numerous tissues including the eye itself, optic nerve, muscles, fat, and much more. The contents of the eye sockets are protected from the elements and held inwards by a membrane called the orbital septum. This membrane extends from the skull to the eyelid margins.

Healthy eye

Frontal view of a healthy eye.


Preseptal cellulitis refers to an infection anterior (in front of) the orbital septum deep in the skin of the eyelids. It is much more common than orbital cellulitis and is usually less worrisome, however, it may lead to more serious conditions such as orbital cellulitis, meningitis, or abscess formation.

Preseptal cellulitis

Frontal view of preseptal cellulitis showing red eyelids.


Orbital cellulitis refers to an infection behind the orbital septum and can be both vision and life threatening. It is most commonly seen in children and usually stems from a sinus infection but can begin through a skin infection, after dental work, from preseptal cellulitis, dacryoadenitis and more.

orbital cellulitis

Frontal view of orbital cellulitis showing a violently red eye, red eyelids, and bulging eye.

Signs and Symptoms

Signs

Preseptal cellulitis

Unilateral (single side of head) swollen and red eyelids.

Orbital cellulitis

Unilateral eyelid and eye swelling, red eyelids and eye, abnormal pupil reaction, bulging eye, optic nerve swelling.

Symptoms

Preseptal cellulitis

Unilateral firm and tender eyelids.

Orbital cellulitis

Unilateral pain, warm and tender eyelids, feeling ill, possible decreased vision, decreased color vision, double vision, pain on eye movement.

Causes and Risk Factors

Causes

Infection.


Risk Factors

Preseptal cellulitis

Skin trauma, insect bite, spread from hordeolum, conjunctivitis.

Orbital cellulitis

Young age (child), skin infections, dental work, preseptal cellulitis, dacryoadenitis.

Prevention and Treatment

Prevention

Seek medical attention for skin, sinus, respiratory tract, and ear infections.


Treatments

Preseptal cellulitis

· Oral antibiotics. · Intravenous antibiotics.

Orbital cellulitis

· Hospital admission and frequent monitoring. · Intravenous antibiotics. · Check tetanus status. · Perform blood cultures to identify bacteria. · CT or MRI of head to look for brain or sinus abscess. · Possible surgery for abscesses.

Prognosis

Preseptal cellulitis is usually an easily treatable condition that requires about 10 days of antibiotics and is not contagious. Orbital cellulitis is vision and life threatening and does necessitate hospital admission and frequent follow ups but timely treatment can drastically increase the odds of a full recovery.

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